Denture-related stomatitis in new complete denture wearers and its association with Candida species colonization: a prospective case-series
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Objectives: To assess the relationship between the development of denture-related stomatitis (DRS) and the identification of commonly isolated yeast species, and to evaluate various predisposing factors in Saudi participants wearing new removable dental prostheses.
Method and materials: A total of 75 edentulous male participants were recruited, and 64 patients finished the present case-series. All participants received new conventional complete dentures. Colonization of Candida species was assessed, and species were identified by means of the VITEK 2 (bioMérieux) laboratory components.
Results: The most prevalent type of Candida at baseline was C albicans, followed by non-C albicans species (C glabrata). Counts of Candida species significantly increased from the day of insertion to the first month (P < . 05), but there were no significant changes between the first and second month (P > . 05). On the day of insertion, C tropicalis, C dubliniensis, and C krusei were extracted from few subjects only, with no significant changes over the first and second month (P > .05). Patients revealing habits of sleeping with their dentures were found to frequently suffer from DRS; development of the latter was rapid, and mixed Candida biofilms (with high CFU/mL counts), along with inadequate oral and denture hygiene, turned out to be contributing factors (P < .05).
Conclusion: DRS can develop faster than previously reported, even with new dentures; continued denture wearing and poor cleaning of dentures revealed a considerable impact on DRS onset. In the present cohort, C albicans was the most identified kind of yeast, and was followed by C glabrata infection in cases with DRS.
Keywords: VITEK 2 Compact system; complete denture; denture hygiene; denture stomatitis; denture-related stomatitis; sleeping with dentures; yeast species; Candida species.
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- Isolation of Candida species from the oral cavity and fingertips of complete denture wearers.J Contemp Dent Pract. 2014 Nov 1;15(6):712-6. doi: 10.5005/jp-journals-10024-1604.PMID: 25825095
- Isolation of Candida dubliniensis from denture wearers.J Med Microbiol. 2009 Jul;58(Pt 7):959-962. doi: 10.1099/jmm.0.008391-0. Epub 2009 Jun 4.PMID: 19498202
- Epidemiology and etiology of denture stomatitis.J Prosthodont. 2011 Jun;20(4):251-60. doi: 10.1111/j.1532-849X.2011.00698.x. Epub 2011 Apr 4.PMID: 21463383 Review.
- Development of Candida-associated denture stomatitis: new insights.J Appl Oral Sci. 2008 Mar-Apr;16(2):86-94. doi: 10.1590/s1678-77572008000200002.PMID: 19089197 Free PMC article.