Antimicrobial activity of denture adhesive associated with Equisetum giganteum- and Punica granatum-enriched fractions against Candida albicans biofilms on acrylic resin surfaces
Candida biofilms adhere to the internal surface of removable dentures. They form part of an etiological factor in the pathogenesis of denture stomatitis (DS). Furthermore, Adhesive materials are used at the base of maxillary complete dentures to improve their retention and chewing qualities. Also, this article reports the antimicrobial activity of the enriched fractions of Equisetum giganteum and Punica granatum incorporated into a denture adhesive against C. Albicans biofilm.
The surface of heat-cured acrylic resin specimens produces the biofilms. In addition,a mixture of adhesive/herb extracts previously treated these biofilms. Furthermore, the CFU counts, XTT reduction, and SEM and CLSM analysis evaluated antimicrobial activity. Likewise, herb extracts amplified the anti-biofilm action of the adhesive on the acrylic resin by up to 12 hours. Therefore, these extracts played a collaborative and innovative role in biofilm control when combined with COREGA®. Moreover, they can be considered alternatives for temporary use in the treatment and/or prevention of DS.
Author information:
(1)a Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of
Dentistry , University of São Paulo , Bauru , Brazil.
(2)b Department of Botany, Institute of Biosciences , São Paulo State University
(UNESP) , Botucatu , Brazil.
(3)c Department of Biological Sciences, Faculty of Sciences , São Paulo State
University (UNESP) , Bauru , Brazil.
(4)d Department of Prosthodontics and Periodontics, Bauru School of Dentistry ,
University of São Paulo , Bauru , Brazil.
Lorin Berland, DDS